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Causes of High Blood Pressure

What causes high blood pressure?
Blood pressure is the measure of the force of blood pushing against blood vessel walls. The heart pumps blood into the arteries (blood vessels), which carry the blood throughout the body. High blood pressure, also called hypertension, is dangerous because it makes the heart work harder to pump blood to the body and contributes to hardening of the arteries, or atherosclerosis, and to the development of heart failure.
What Is "Normal" Blood Pressure?
A blood pressure reading has a top number (systolic) and bottom number (diastolic). The ranges are:
·         Normal: Less than 120 over 80 (120/80)
·         Prehypertension: 120-139 over 80-89
·         Stage 1 high blood pressure: 140-159 over 90-99
·         Stage 2 high blood pressure: 160 and above over 100 and above
·         High blood pressure in people over age 60: 150 and above over 90 and above
People whose blood pressure is above the normal range should consult their doctor about steps to take to lower it.
What Causes High Blood Pressure?
The exact causes of high blood pressure are not known, but several factors and conditions may play a role in its development, including:
·         Smoking
·         Being overweight or obese
·         Lack of physical activity
·         Too much salt in the diet
·         Too much alcohol consumption (more than 1 to 2 drinks per day)
·         Stress
·         Older age
·         Genetics
·         Family history of high blood pressure
·         Chronic kidney disease
·         Adrenal and thyroid disorders



Types of high blood pressure
Essential Hypertension
In as many as 95% of reported high blood pressure cases in the U.S., the underlying cause cannot be determined. This type of high blood pressure is called essential hypertension.
Though essential hypertension remains somewhat mysterious, it has been linked to certain risk factors. High blood pressure tends to run in families and is more likely to affect men than women. Age and race also play a role. In the United States, blacks are twice as likely as whites to have high blood pressure, although the gap begins to narrow around age 44. After age 65, black women have the highest incidence of high blood pressure.
Essential hypertension is also greatly influenced by diet and lifestyle. The link between salt and high blood pressure is especially compelling. People living on the northern islands of Japan eat more salt per capita than anyone else in the world and have the highest incidence of essential hypertension. By contrast, people who add no salt to their food show virtually no traces of essential hypertension.
The majority of all people with high blood pressure are "salt sensitive," meaning that anything more than the minimal bodily need for salt is too much for them and increases their blood pressure. Other factors that can raise the risk of having essential hypertension include obesity; diabetes; stress; insufficient intake of potassium, calcium, and magnesium; lack of physical activity; and chronic alcohol consumption.
Secondary Hypertension
When a direct cause for high blood pressure can be identified, the condition is described as secondary hypertension. Among the known causes of secondary hypertension, kidney disease ranks highest. Hypertension can also be triggered by tumors or other abnormalities that cause the adrenal glands (small glands that sit atop the kidneys) to secrete excess amounts of the hormones that elevate blood pressure. Birth control pills -- specifically those containing estrogen -- and pregnancy can boost blood pressure, as can medications that constrict blood vessels.
Who Is More Likely to Develop High Blood Pressure?
·         People with family members who have high blood pressure
·         Smokers
·         African-Americans
·         Pregnant women
·         Women who take birth control pills
·         People over the age of 35
·         People who are overweight or obese
·         People who are not active
·         People who drink alcohol excessively
·         People who eat too many fatty foods or foods with too much salt
·         People who have sleep apnea



Symptoms of high blood pressure
Most people with high blood pressure don't have any symptoms, so you may only find out you have high blood pressure by having it checked.
If you have very high blood pressure, or your blood pressure rises quickly, you may have headaches, problems with your vision, fits or black-outs – but this is very uncommon.
Complications of high blood pressure
If you have high blood pressure, you have an increased risk of major illnesses including:
·         cardiovascular disease, such as angina (chest pain caused by reduced blood flow),strokeheart attackheart failure or atrial fibrillation (irregular heart beat)
·         kidney damage
·         damaged sight
Causes of high blood pressure
Depending on the cause, high blood pressure can be diagnosed as primary or secondary hypertension.
Primary hypertension
About 95 in 100 people with high blood pressure have primary hypertension. This means there is no single cause, but various lifestyle factors can contribute, including:
·         smoking
·         obesity (being very overweight)
·         drinking alcohol excessively – especially if you binge drink
·         lack of exercise
·         your diet, particularly salt intake
If someone else in your family has high blood pressure, you also have a higher risk of developing it.
Secondary hypertension
About five in 100 people with high blood pressure have secondary hypertension. This means there is a known underlying cause – examples include:
·         kidney disease
·         endocrine disease (hormone disorders)
·         a narrowing of part of your aorta (the largest artery leading from your heart) or the arteries leading to your kidneys
Secondary hypertension can also be caused by:
·         steroid medicines
·         the contraceptive pill
·         pregnancy, which can lead to pre-eclampsia – this can be serious and harm your baby
Diagnosis of high blood pressure
Your GP may diagnose you with high blood pressure when he or she measures it as part of a medical examination. This is a good reason to have regular check-ups with your GP, especially if you're over 40.
Your GP or nurse will measure your blood pressure with a sphygmomanometer. He or she will place a cuff around your upper arm, inflate it to a certain level and then deflate it slowly. Your blood pressure is measured in mmHg, or millimeters of mercury. The blood pressure monitor will provide a reading as two numbers, one number on top of the other, such as 120/80mmHg (one hundred and twenty over eighty millimeters of mercury).
·         The first figure is called systolic blood pressure. This is a measure of the pressure when your heart muscle is contracted and pumping blood out of your heart. This is the highest pressure in your blood vessels.
·         The second figure is called diastolic blood pressure. This is the pressure between heart beats when your heart is resting and filling with blood. This is the lowest pressure in your blood vessels.
Generally speaking, the lower your blood pressure, the better it is for your health. For people under the age of 80, doctors recommend your blood pressure is kept below 140/90 measured in the clinic, or 135/85 measured at home. A slightly higher level is acceptable for people over 80. If you have diabetes, kidney disease or cardiovascular disease, your blood pressure should be lower than this – ideally less than 130/80.
Your GP may ask you to come back for repeat measurements over a number of weeks and arrange a 24-hour blood pressure recording before suggesting you have treatment. This is so he or she can check that the high reading is an ongoing problem and not a one-off.
You may also need some tests to see if high blood pressure is affecting the rest of your body. These may include:
·         a urine test – protein in your urine may be the first sign of damage to your kidneys
·         a blood test to check your cholesterol and blood sugar levels, as well as the condition of your kidneys
·         an electrocardiogram (ECG) – a test that measures the electrical activity of your heart to check for signs of heart enlargement or other damage


Monitoring
If you have a high blood pressure reading, you may be given 24-hour ambulatory blood pressure monitoring (ABPM). This is because some people have a high reading when they see a doctor, but normal blood pressure at other times (so-called ‘white coat hypertension’). A monitoring device is strapped around your waist and attached to a cuff, which is wrapped around your upper arm. The cuff inflates and deflates automatically and takes recordings of your blood pressure throughout the 24 hours. You can carry on with your usual activities whilst wearing the monitor, except for having a bath or shower. Your GP will use the measurements to find out your average blood pressure.
In some cases, another form of home blood pressure monitoring (HBPM) may be used to confirm your diagnosis. Your GP may provide a blood pressure monitor for you to record your blood pressure twice a day at home, in the morning and evening, for four to seven days.
You might also consider getting a blood pressure monitor to use yourself at home on a regular basis. This can help you identify situations or activities in your daily life that cause your blood pressure to rise. And if you’re having treatment for blood pressure, it may also help you to see how your treatment is working. Even if you use a blood pressure monitor at home, you should continue to have your blood pressure tested regularly by your GP.
Treatment of high blood pressure
If you need treatment, it’s likely to be long-term as high blood pressure can’t usually be cured. You may need to go to hospital for treatment if you have very high blood pressure, but it's more likely that your GP and/or a nurse will look after you.
Self-help
Your GP or nurse will talk to you about lifestyle changes that might help, such as:
·         stopping smoking
·         changing your diet to be low-fat, low-salt and that includes fruit and vegetables
·         cutting down on alcohol
·         cutting down on coffee and high-caffeine drinks, such as cola
·         taking regular, aerobic exercise
·         losing any excess weight
It may also help, where possible, to reduce stress in your life to prevent short-term rises in blood pressure – you could try relaxation techniques or meditation.
Medicines
If your blood pressure stays high, your GP may prescribe you one or more of the following antihypertensive medicines.
·         ACE inhibitors (eg ramipril) or angiotensin-II receptor antagonists (eg candesartan) – these relax and widen the walls of your blood vessels by reducing the production of hormones that cause your blood vessels to constrict (narrow).
·         Calcium-channel blockers (eg amlodipine) – these help to widen your blood vessels by relaxing the muscles in your blood vessel walls.
·         Diuretics (eg indapamide) – these increase the amount of water and salt removed from your blood by your kidneys, lowering the volume of your blood, which reduces blood pressure.
If your symptoms don’t improve, then your GP may prescribe one of the following.
·         Beta-blockers (eg atenolol) – these reduce the work your heart has to do by reducing your pulse rate and the force of contraction of your heart at rest and when you exercise.
·         Alpha-blockers (eg doxazosin) – these help to widen your blood vessels by relaxing the muscles in your blood vessel walls.
The medicines your GP prescribes will depend on a number of factors, including your age and ethnicity. It may take time to find the best treatment for you; one that balances the benefits against any side-effects.
It's important to take your medicines every day, even if you don't have any symptoms.
Special considerations
Pregnancy
If you're pregnant, your blood pressure will be monitored regularly, regardless of whether you have high blood pressure or not. Long-term high blood pressure may be picked up at an antenatal appointment. It's also possible that you may develop high blood pressure during your pregnancy (gestational hypertension). High blood pressure that develops after 20 weeks of pregnancy can mean you have pre-eclampsia.
If you have high blood pressure and think you may be, or are trying to become pregnant, it's important to speak to your GP. Certain medicines for treating high blood pressure aren't suitable for pregnant women.
Ethnic groups
If you're of African-Caribbean origin, you're at a higher risk of high blood pressure and should visit your GP to discuss how often you need to have your blood pressure checked.
You should also be monitored regularly if you're of South-Asian origin because you have a higher risk of developing heart disease and diabetes.

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